By Miles CooperMay 6, 2026 Crime 1. Chicago Records 13th Straight Year as the U.S. City with the Most Murders 2. For the 13th Year Running, Chicago Leads U.S. Cities in Murders 3. Chicago’s Streak: 13 Consecutive Years Topping U.S. Murder Rates 4. Alarming Trend: Chicago Tops Natio Chicago has held the grim distinction of having the highest number of murders in the U.S. for 13 straight years, according to Leavitt. The city continues to grapple with persistent violence despite ongoing efforts to curb crime.